Complement, infection, and autoimmunity

Complement regulatory proteins and autoimmunity.

To discriminate self from non-self is an essential issue in the immune system. Autologous cells are protected against complement-mediated cell injury by the self-recognition mechanism using complement regulatory proteins composed of complement receptor type 1 (CR1, CD35), membrane cofactor protein (MCP, CD46), decay accelerating factor (DAF, CD55) and homologous restriction factor (protectin, C...

Infection and Autoimmunity

Infection and Autoimmunity

As the editors imply in their introduction, the relationship of infection and autoimmunity is complex, compelling, and best viewed as a physiologic process and potential consequence of normal immune recognition and immunoregulation. The editors boldly state that reading the chapters in this book brings one to the conclusion that all autoimmune diseases are infectious, until proven otherwise (my...

HBV infection, vaccination and autoimmunity

• Vol 10 • January 2008 HBV: Infection, Vaccination and Autoimmunity The idea that infectious agents in general, and viruses in particular, could trigger the development of autoimmune diseases in genetically susceptible individuals has been raised in various clinical and epidemiological studies [1]. Also included in the medical literature are case reports, ecological association studies, as wel...

acute and chronic maxillary sinusitis (nonodontogenic infection)

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